Medication-Induced Hyperprolactinemia

Antipsychotic-induced hyperprolactinemia.

Use of antipsychotic agents has been associated with hyperprolactinemia, or elevated prolactin levels; this hormonal abnormality can interfere with the functioning of reproductive, endocrine, and metabolic systems. As antipsychotic agents are increasingly used for both United States Food and Drug Administration-approved and nonapproved indications, many individuals are at risk for developing an...

P-224: Chlropromazine-Induced Hyperprolactinemia on Rat

Unusually high prolactin level for medication-induced hyperprolactinemia: a case report.

Hyperprolactinemia has a number of etiologies, including physiological, pathological and pharmacological causes. Hyperprolactinemia is frequently associated with the use of certain medications. Patients using medications known to cause hyperprolactinemia generally develop a mild form of the condition, and the prolactin level rarely exceeds 100 ng/mL in these cases. We report a case of a 43-year...

Aripiprazole reverses paliperidone-induced hyperprolactinemia.

Hyperprolactinemia is a common side effect of antipsychotic treatments. Existing alternatives to resolve this problem include decreasing the antipsychotic dose or switching to a different antipsychotic agent. Nevertheless, said modifications can sometimes lead to decompensation of the patient. We report a clinical case of a female patient in whom the combined treatment of 5 mg/day of aripiprazo...

Chlorpromazine-Induced Hyperprolactinemia on Rat’s Uterus

Background: Hyperprolactinemia is a common side effect of antipsychotic drugs that requires further investigation. The current study was designed to evaluate dose-dependent effect of chlorpromazine (CPZ) on hormonal changes and uterine horn histological structure in rats. Moreover, the mammary glands were analyzed to show hyperprolactinemia-induced histological changes. Methods: Albino Wistar r...